ALB, albumin, 213

N. diseases: 1198; N. variants: 21
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0239981
Disease: Hypoalbuminemia
Hypoalbuminemia
0.500 AlteredExpression disease BEFREE Hip fracture patients who underwent THA and had preoperative hypoalbuminemia (<3.5 g/dL) (<i>n</i> = 569) were compared to those who had normal albumin levels (⩾3.5 g/dL) (<i>n</i> = 1098) in terms of demographics and perioperative data. 31304789 2019
CUI: C0239981
Disease: Hypoalbuminemia
Hypoalbuminemia
0.500 AlteredExpression disease BEFREE We observed significantly worse patient survival (83.2% vs 90.7%, P < 0.001) and overall graft survival (72.5% vs 82.0%, P < 0.001) for recipients with hypoalbuminaemia vs normal albumin levels, respectively, but no difference in death-censored graft survival. 30152018 2019
CUI: C0239981
Disease: Hypoalbuminemia
Hypoalbuminemia
0.500 AlteredExpression disease BEFREE Anemia was defined when hemoglobin was <12 g/dL for women and <13 g/dL for men, and hypoalbuminemia when serum albumin was <3.5 g/dL. 28782162 2018
CUI: C0239981
Disease: Hypoalbuminemia
Hypoalbuminemia
0.500 AlteredExpression disease BEFREE Shorter overall survival (OS) was observed in patients with hypoalbuminemia (5-year OS rate 17.1%) when compared to patients with normal serum albumin levels (5-year OS rate 58.6%, p = 0.004). 31468203 2019
CUI: C0239981
Disease: Hypoalbuminemia
Hypoalbuminemia
0.500 AlteredExpression disease BEFREE Two weeks after commencing treatment with IVIG (2 g/kg), the median serum albumin level decreased to 3.7 g/dL (interquartile range, 3.2-4.1 g/dL) (P < .001), and the number with hypoalbuminemia increased to 60 (34.5%) of 174 (P < .001). 28027337 2017
CUI: C0239981
Disease: Hypoalbuminemia
Hypoalbuminemia
0.500 AlteredExpression disease BEFREE Patients were stratified by preoperative albumin level, with less than 3.5 g/dL indicating hypoalbuminemia. 30222797 2018
CUI: C0239981
Disease: Hypoalbuminemia
Hypoalbuminemia
0.500 AlteredExpression disease BEFREE Hemoglobin and albumin were significantly lower (9.72±1.9 vs. 12.2±1.8; P=.004 and 3.6±0.5 vs. 4.0±0.3; P=.035) and the proportion of patients with anemia and hypoalbuminemia was significantly higher (85.7% vs. 37.5%; P=.019 and 61.9% vs. 12.5%; P=.035) in patients with increased E/e'. 30032857 2019
CUI: C0239981
Disease: Hypoalbuminemia
Hypoalbuminemia
0.500 AlteredExpression disease BEFREE Last, there were higher rates of extra-intestinal, non-septic complications in both CD and UC patients with hypoalbuminaemia compared with those with normal albumin levels. 31253985 2019
CUI: C0239981
Disease: Hypoalbuminemia
Hypoalbuminemia
0.500 AlteredExpression disease BEFREE Hypoalbuminemia as assessed by the nadir albumin level was associated with an increased risk of acute worsening of renal function. 29865919 2018
CUI: C0239981
Disease: Hypoalbuminemia
Hypoalbuminemia
0.500 AlteredExpression disease BEFREE When compared with normal albumin level (>40.0g/L), severe (≤30.0g/L: OR 2.727, 95% CI 1.283-5.797, P=0.009), but not mild (35.1-40.0g/L: OR 1.175, 95% CI 0.679-2.032, P=0.565) or moderate (30.1-35.0g/L: OR 1.674, 95% CI 0.897-3.122, P=0.105) hypoalbuminemia was associated with an increased risk of postoperative delirium. 29055835 2018
CUI: C0239981
Disease: Hypoalbuminemia
Hypoalbuminemia
0.500 AlteredExpression disease BEFREE A total of 5143 patients met inclusion criteria; 4397 (85.5%) patients had a normal albumin level while 746 (14.5%) had hypoalbuminemia. 27612919 2017
CUI: C0239981
Disease: Hypoalbuminemia
Hypoalbuminemia
0.500 AlteredExpression disease BEFREE Pre-operative serum albumin level may therefore be used as a continuous rather than a categorical marker of disease severity, especially among patients with hypoalbuminaemia. 26526411 2017
CUI: C0239981
Disease: Hypoalbuminemia
Hypoalbuminemia
0.500 AlteredExpression disease BEFREE Low serum albumin levels (hypoalbuminemia) have classically been used to identify malnutrition. 29558371 2018
CUI: C0239981
Disease: Hypoalbuminemia
Hypoalbuminemia
0.500 AlteredExpression disease BEFREE Diagnostic cut-off level of Hypo-A (< 2.8 mg/dl) was determined using the ROC curve between blood albumin and mortality. 30729384 2019
CUI: C0239981
Disease: Hypoalbuminemia
Hypoalbuminemia
0.500 AlteredExpression disease BEFREE Patients with post-treatment hypoalbuminemia had significantly shorter median PFS (6 months [95% CI 5-7 months]) and OS (11 months [95% CI 9-15 months]) than patients who had normal post-treatment albumin levels (PFS: 12 months [95% CI 11-16 months], P < 0.001; OS: 31 months [95% CI 24-42 months], P < 0.001), respectively. 28521783 2017
CUI: C0239981
Disease: Hypoalbuminemia
Hypoalbuminemia
0.500 AlteredExpression disease BEFREE We collected data on surgical factors, perioperative levels of serum albumin and inflammatory markers, and perioperative factors affecting hypoalbuminemia from 196 CRC patients to assess the relation to anastomotic leakage. 27451010 2018
CUI: C0239981
Disease: Hypoalbuminemia
Hypoalbuminemia
0.500 AlteredExpression disease BEFREE Survival analysis showed that patients with persistently normal albumin levels had the highest survival rates at 6 months (97.7%), compared with patients who had hypoalbuminemia at index admission but normalised their albumin levels in subsequent admissions (92%), patients with declining albumin trends (85.6%) and patients with persistently low albumin levels (68.9%) (P < 0.0001). 30664804 2019
CUI: C0239981
Disease: Hypoalbuminemia
Hypoalbuminemia
0.500 AlteredExpression disease BEFREE Hypoalbuminemia was defined as serum albumin level <3.5 g/dl. 28017301 2017
CUI: C0239981
Disease: Hypoalbuminemia
Hypoalbuminemia
0.500 AlteredExpression disease BEFREE Patients with hypoalbuminemia had higher mortality than patients with normal albumin levels (48% vs. 23%, p = 0.004). 31095609 2019
CUI: C0239981
Disease: Hypoalbuminemia
Hypoalbuminemia
0.500 AlteredExpression disease BEFREE We hypothesized that sucroferric oxyhydroxide (SO), a potent phosphate binder with a low pill burden, may reduce serum phosphorus levels in hemodialysis patients with hypoalbuminemia without adversely impacting albumin levels or dietary intake of protein. 31664928 2019
CUI: C0239981
Disease: Hypoalbuminemia
Hypoalbuminemia
0.500 AlteredExpression disease BEFREE Patients with hypoalbuminemia at diagnosis had a higher likelihood of ≥ 2 courses of CS use (adjusted HR = 1.7, 95%CI: 1.3-2.3), higher likelihood of thiopurine or anti- TNF use (adjusted HR = 1.72, 95%CI: 1.23-2.40) than patients with normal albumin level at diagnosis. 29259376 2017
CUI: C0239981
Disease: Hypoalbuminemia
Hypoalbuminemia
0.500 Biomarker disease BEFREE The SUV<sub>mean</sub> of the mediastinal blood uptake in patients with hypoalbuminemia and normal serum albumin were 1.6 ± 0.2 and 1.7 ± 0.3, respectively (p = 0.053). 31201673 2019
CUI: C0239981
Disease: Hypoalbuminemia
Hypoalbuminemia
0.500 Biomarker disease BEFREE The 2005-2012 National Surgical Quality Improvement Program was analyzed to determine associated complications, mortality, length of stay (LOS), and readmissions for patients with hypoalbuminemia (serum albumin <3.5 g/dL and <2.8 g/dL) undergoing infrainguinal lower extremity bypass for critical limb ischemia. 28242402 2017
CUI: C0239981
Disease: Hypoalbuminemia
Hypoalbuminemia
0.500 Biomarker disease BEFREE The effect of having hypoalbuminemia (defined as albumin ≤3.5 g/dL) on selected outcomes was examined using fully adjusted multivariable models. 30481611 2018
CUI: C0239981
Disease: Hypoalbuminemia
Hypoalbuminemia
0.500 Biomarker disease BEFREE Multivariate logistic regression analyses showed that HD duration, the normalized protein catabolic rate (nPCR), hypoalbuminemia (albumin < 4 g/dl), and the mean previous 12-month environmental PM2.5 were positively associated with CTS; HD duration, nPCR, hypoalbuminemia (albumin < 4 g/dl), and the mean previous 24-month environmental PM2.5 were positively associated with CTS; HD duration, hypoalbuminemia (albumin < 4 g/dl), and previous 12-month PM2.5 excess days were positively associated with CTS; and HD duration, nPCR, hypoalbuminemia (albumin < 4 g/dl), and previous 24-month PM2.5 excess days were positively associated with CTS. 29161700 2017